Dermatomyositis, three doctors facing the camera smiling with their arms crossed

What is


Dermatomyositis is an inflammatory muscle disease characterised by skeletal muscle weakness and changes to the skin. The condition is uncommon and can affect people of any race, age and gender but appears to be twice as common in women.

A face rash is the most common initial skin sign, typically followed by scalp symptoms and changes on the hands. Other skin changes of dermatomyositis include:

  • Discolouration and swelling (called heliotrope) of the eyelids
  • A greyish-red shawl-like rash over the neck, shoulders, and upper chest and back
  • Redness over the backs of the hands, elbows, and knees
  • Smooth or scaly rash around the joints, especially fingers (called Gottron’s sign)
  • Changes to the nail fold
  • Photosensitivity on sun-exposed body areas
  • Itchy scaly scalp with inflammation and thinning of the hair

Dermatomyositis may resolve in 20% of adults who have the condition, but most will require lifelong treatment.


THE Dermatomyositis

  • 35-day screening period
  • 8 scheduled treatment visits lasting approximately 1 hour each
  • 5 monthly follow visits
  • There is no cost to participate
  • Participants will receive travel reimbursement for all attended visits

Approved participants will gain access to an investigative product, have their health and wellbeing monitored throughout the study cost and be reimbursed for travel for each visit.

Dermatomyositis Trails
A diverse group of people smiling at the camera in a group photo


We Are Looking For

  • Aged 18 to 80 years old
  • Lives in Victoria
  • Has been diagnosed with moderate-to-severe dermatomyositis

Sounds like you? Apply now

Why should YOU

Participate In a
Clinical Trial?


To potential new treatment years before they
are publicly available.


Potential relief for your condition long before successful
treatments become readily available.


Regular medical care during the trial.


A more active role in your own health care.


Researchers learn more about certain health problems to advance
treatment and care.


A partner in scientific discovery and contribute to help future
generations lead healthier lives.


For your travel-related expenses and time.

Professor Rodney Sinclair


SincLair Dermatology

Sinclair Dermatology was founded by internationally renowned dermatologist, Professor Rodney Sinclair. In 2010, Sinclair Dermatology established Australia’s largest dedicated Dermatology Investigational Research Education, and Clinical Trials Centre (DIRECT) to reinforce its commitment to excellence in patient care, clinical research and to the development of new treatments to improve patients’ lives.

Since its formation, DIRECT has conducted more than 100 global sponsored Phase I, Phase II, Phase III and Phase IV clinical trials contributing to the treatment and advancement of care for many people with skin and hair disease.



Our centre is located two kilometres from Melbourne CBD

Travelling by car

Free timed street parking is available outside our centre and on the
surrounding streets. Please take note of the parking restrictions.

Travelling by bus

Bus no 246 stops on the corner of Wellington Parade & Hoddle St

Travelling by tram

Tram numbers 48 and 75 stop at the corner of Punt Rd and Wellington
Parade, stop number 14.

Travelling by train

Jolimont and Richmond West train station are within 200 metres
from our centre.

Location, Google Maps view

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